Ceta-T Tablets

Description

The product is  Ceta-T Tablets. Here’s a detailed description based on the information in the box:

Ceta-T Tablets contain:

• Paracetamol (325 mg)
• Tramadol HCl (37.5 mg)

These tablets are an over-the-counter medication designed to provide relief from:

• Headaches
• Muscle aches
• Fever
• General discomfort
• Key features:
• Easy to swallow
• Fast-acting to alleviate discomfort
• Gentle on the stomach
• Effective pain relief solution

Paracetamol and Tramadol are often combined in a single medication to provide effective pain relief. This combination is commonly prescribed for moderate to severe pain when paracetamol alone is insufficient.

Composition and Mechanism of Action

1. Paracetamol (Acetaminophen)
   • Works by inhibiting prostaglandin production in the brain, which reduces pain and fever.
   • It is an effective analgesic (pain reliever) and antipyretic (fever reducer).
   • Does not have anti-inflammatory properties like NSAIDs.
2. Tramadol
   • A centrally acting opioid analgesic that works on the brain to change how the body feels and responds to pain.
   • Also increases serotonin and norepinephrine levels, which contribute to pain modulation.

Uses of Paracetamol + Tramadol Combination

This combination is used to treat conditions involving moderate to severe pain, such as:

• Post-surgical pain
• Chronic pain (e.g., osteoarthritis, rheumatoid arthritis)
• Neuropathic pain (nerve-related pain, such as sciatica)
• Musculoskeletal pain (e.g., back pain, fractures, sprains)
• Cancer pain
• Dental pain

Dosage & Administration

• Typically available as 37.5 mg Tramadol + 325 mg Paracetamol per tablet.
• Usually taken every 6-8 hours, but dosage varies based on the severity of pain and patient tolerance.
• Maximum daily dose: 8 tablets (300 mg Tramadol & 4,000 mg Paracetamol).

Side Effects

Effects of an Overdose of Ceta-T Tablets with Paracetamol and Tramadol

Taking an extra or excessive dose of Paracetamol + Tramadol can be dangerous and may lead to serious health complications, including liver failure, respiratory depression, seizures, and even death.

1. Overdose Effects of Ceta-T Tablets

Safe dose: Maximum 4,000 mg (4g) per day for adults.
Toxic dose: More than 7,500 mg (7.5g) in a day can cause liver damage.

Symptoms of Paracetamol Overdose

• Early Symptoms (First 24 hours):
  • Nausea, vomiting, stomach pain
  • Loss of appetite
  • Sweating
  • Fatigue
• Severe Symptoms (24-72 hours after overdose):
  • Liver damage/failure (yellowing of the skin, dark urine, abdominal pain)
  • Confusion
  • Bleeding disorders
  • Coma (in extreme cases)

Treatment:

• Immediate medical help is necessary.
• N-Acetylcysteine (NAC) is the antidote used to prevent liver damage if given within 8-10 hours of overdose.

2. Overdose Effects of Ceta-T Tablets Tramadol

Safe dose: Maximum 400 mg per day (for healthy adults).
Toxic dose: More than 500 mg in a day can cause serious complications.

Symptoms of Tramadol Overdose

• Mild to Moderate Symptoms:
  • Dizziness, nausea, vomiting
  • Excessive drowsiness
  • Weakness
• Severe Symptoms:
  • Respiratory depression (slow or difficult breathing)
  • Seizures (high risk, especially in overdose)
  • Coma or unconsciousness
  • Serotonin syndrome (agitation, high body temperature, sweating, confusion, increased heart rate)

Treatment:

• Naloxone (opioid antidote) may be given in severe cases to reverse respiratory depression.
• Supportive care, including oxygen therapy, IV fluids, and seizure management.

What to Do in Case of Overdose of Ceta-T Tablets?

1. Seek emergency medical help immediately (Call an ambulance or go to the nearest hospital).
2. Do NOT wait for symptoms to appear, as liver or brain damage can occur gradually.
3. If conscious, the person may be given activated charcoal (to reduce drug absorption).

Conclusion

Paracetamol overdose mainly affects the liver, while Tramadol overdose can cause breathing problems, seizures, and coma.
If an overdose is suspected, immediate medical intervention is critical to prevent life-threatening complications.

• Common: Nausea, dizziness, drowsiness, constipation, headache.
• Serious: Respiratory depression, liver damage (due to excessive paracetamol), serotonin syndrome (when taken with antidepressants).

Precautions

• Not suitable for patients with liver disease, kidney impairment, or a history of opioid addiction.
• Avoid alcohol and other sedatives, as they can increase drowsiness and risk of overdose.
• Should not be used in children under 12 years or in patients with respiratory issues.

Conclusion

The Paracetamol + Tramadol combination is a powerful pain reliever for moderate to severe pain. However, it should be used with caution due to the risk of opioid dependence, liver toxicity, and side effects. Always follow a doctor’s prescription when using this medication.

The packaging highlights that these tablets are a convenient and effective option for managing pain.

For further information, the image references the manufacturer’s website: www.hassnipharma.com.