Introduction of itopride

Itopride is an efficiently increases movement of food and facilitates emptying of the stomach. It is used for the treatment of Gastroesophageal Reflux Disease, Functional Dyspepsia, and other associated motility disorders.

Uses of Itopride

What is it prescribed for?

Non-ulcer dyspepsia

Itopride is used for the treatment of non-ulcer or functional dyspepsia. Symptoms may include fullness, discomfort and sometimes pain of the stomach.

Gastroparesis

Itopride is used for the treatment of condition where movement of food from the stomach is very slow resulting in delayed emptying.

Nausea and vomiting

Itopride is also sometimes used for the prevention and treatment of nausea and vomiting. This may be due to chemotherapy or a recent surgery.

Concerns

Onset of action

The effect of this medicine can be observed within 30-60 minutes of administration.

Duration of effect

The effect of this medicine lasts for 4-6 hours. However, it is subject to vary from one patient to another.

Safe with alcohol?

Reduce or minimize the uptake of alcohol while taking this medicine. Contact your doctor if any unwanted effects are observed.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

Use of this medicine in pregnant women is not recommended unless absolutely necessary. It should be used only if the potential benefits outweigh the associated risks. Consult your doctor before taking this medicine.

Usage while breast-feeding?

Use of this medicine in breastfeeding mothers is not recommended. If the need of this medicine is absolutely necessary then breastfeeding should be discontinued prior to uptake. Consult your doctor before taking this medicine.

• Side effects

Major & minor side effects for Itopride

• Diarrhea

• Abdominal pain

• Headache

• Nausea

• Decrease in white blood cells and platelet ts

• Gynecomastia

• Allergic skin reaction

• Increased liver enzyme levels

• Jaundice

When not to use?

Allergy

This medicine is not recommended for use in patients with a known history of allergy to Itopride or any other ingredient present along with it.

Gastrointestinal haemorrhage

This medicine is not recommended for use in patients having internal bleeding of the stomach and intestine. This may be attributed to various reasons including a ruptured bowel (Gastrointestinal Perforation).

Mechanical bowel obstruction

This medicine is not recommended for use in patients having a blockage in the intestine.

Parkinson’s disease

This medicine is not recommended for use in patients having dopamine related disorders like Parkinson’s disease.

Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped.

Overdose

The likelihood of an overdose is very less. However, contact your doctor if an overdose is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Use of alcohol in excessive amounts can cause acidity and the risk of adverse effects are very high while taking it with this medicine.

Instructions

Reduce or minimize the uptake of alcohol while taking this medicine. Contact your doctor if any unwanted effects are observed.

Interaction with Medicine

Anticholinergic drugs

Disease interactions

Disease

Information not available.

Food interactions

It is advised to not consume grapefruit juice in large quantities while taking this medicine as the likelihood of unwanted effects increase. Consult your doctor if an undesirable effect is experienced.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

Warnings

Warnings for special population

Pregnancy

Use of this medicine in pregnant women is not recommended unless absolutely necessary. It should be used only if the potential benefits outweigh the associated risks. Consult your doctor before taking this medicine.

Breast-feeding

Use of this medicine in breastfeeding mothers is not recommended. If the need of this medicine is absolutely necessary then breastfeeding should be discontinued prior to uptake. Consult your doctor before taking this medicine.

General warnings

Pediatric use

Use of this medicine is not recommended in children who are less than 16 years old.

Geriatric use

This medicine should be used with caution in elderly patients as the risk of side effects are increasingly high.

Bleeding of stomach and intestine

Report any instance indicating bleeding of the stomach like presence of blood in stools, black or coffee colored stools to the doctor. This medicine should not be used if bleeding is evident or even suspected.

Mechanical obstruction of stomach

Report any incidence indicating intestinal blockage like severe bloating, nausea, vomiting, severe abdominal cramps, constipation etc to the doctor. Use of this medicine is not recommended in such cases.

Other medicine

Report the use of all other medicine including supplements and herbs to the doctor while receiving this medicine.

Other details

• Miscelleneous

• To be taken before food

• To be taken as instructed by doctor

• May cause sleepiness

How it works

This medicine acts by increasing the concentration of chemicals at the nerve endings causing an increase in stomach muscle movement. This helps in the faster movement of food from the stomach to the intestine.

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